Estimation of Serum Level of Omentin-1 in Hirsute Females: A Single Center Study

    October 2022 in “ The Egyptian Journal of Hospital Medicine ”
    Mariam Mohamed Elbhoty, Hassan Abd-elraheem Fayed, Hamdi Fouad Ali Ebrahim, Heba Ahmed Abdel-Azeem
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    TLDR Females with idiopathic hirsutism have higher levels of omentin-1, which may lead to excessive hair growth.
    The study "Estimation of Serum Level of Omentin-1 In Hirsute Female: A Single Center Study" involved 42 females with hirsutism (21 idiopathic, 21 with polycystic ovary syndrome (PCOS)) and 42 healthy controls. The research aimed to evaluate the serum level of omentin-1, a protein that potentially stimulates hair growth, in hirsute females compared to non-hirsute females. The results showed that hirsutism with PCO subgroup had significantly lower dehydroepiandrosterone sulphate (DHEA-S), higher testosterone (TT), fasting blood glucose (FBG), fasting insulin, HOMA-IR compared to those with idiopathic hirsutism. Higher omentin-1 level was significantly associated with idiopathic hirsutism compared to hirsutism with PCO subgroups (mean= 309.7 versus 184.6, p < 0.001). The study concluded that in females with idiopathic hirsutism, serum omentin-1 is increased, and this rise may contribute to excessive hair growth.
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