September 2025 in “Aesthetic Surgery Journal” In this systematic review and meta-analysis, researchers found that exosome therapies significantly improved facial wrinkles by 20.2% and enhanced hair density and thickness by 23.6% and 18%, respectively, despite challenges in generalizability due to study heterogeneity and nonstandardized protocols.
This abstract compiles a list of medical syndromes and conditions related to tongue abnormalities and other systemic features but reports no new research findings.
22 citations
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March 2017 in “Journal of the Formosan Medical Association” This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
January 1999 in “Universitas Philosophica” This study found that cornifin-alpha/SPRR1 expression in mouse skin increases significantly in response to phorbol ester treatment and in papillomas and squamous cell carcinomas, particularly in differentiated areas.
May 2026 in “Applied Spectroscopy” This study used Raman spectroscopy and wide-angle X-ray scattering to observe two main α-helix to β-sheet transitions in hair keratin under varying humidity levels, finding that water impacts when these structural changes occur, involving a disordered state.
37 citations
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November 2024 in “Cosmetics” This review examines the promising role of nanocarriers, specifically liposomes and ethosomes, in enhancing transdermal drug delivery for skin diseases. Ethosomes, highlighted for their ability to penetrate deeper skin layers, show potential for more effective treatments but require further clinical investigation.
17 citations
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October 2017 in “Scientific reports” This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.
4 citations
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August 2014 in “Journal of molecular structure” In this study, the authors concluded that a hydrolyzed eggwhite protein treatment promoted the reconnection of disulfide bonds in excessively bleached hair, after reduction and oxidation processes in permanent waving.
43 citations
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August 2016 in “International Journal of Nanomedicine” This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.
February 2026 in “Molecular and Cellular Probes” This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, exosome-like nanoparticles derived from rose stem cell culture were found to enhance skin quality by increasing collagen production, reducing melanin and inflammation, and promoting cell migration in vitro, suggesting potential aesthetic applications.
June 2011 in “Oncology times” This article outlines the author's personal strategies for managing dermatological toxicities, such as acneiform rash and dry skin, associated with EGFR inhibitor therapy; it does not present new research findings.
46 citations
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April 2005 in “Melanoma Research” This article compiles various methods and models for studying keratinocytes, epidermal stem cells, and differentiation processes, but it reports no new research findings.
This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.
323 citations
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November 1984 in “Journal of Investigative Dermatology”
September 2009 in “Dermato-endocrinology” This summary discusses the role of endocrinology and nutrition in skin health, highlighting the importance of a balanced approach to UV exposure, nutrition, and potential benefits of probiotics without reporting new research findings.
In this study, exosome-loaded hydrogels derived from skin precursor cells significantly improved wound healing in diabetic rats by enhancing angiogenesis, reducing inflammation, and promoting tissue repair.
14 citations
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November 2018 in “Journal of drug delivery and therapeutics” This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.
38 citations
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April 2017 in “PLOS Genetics” This study found that human progenitor keratinocytes form unique complements of enhancers and super-enhancers during differentiation and migration, influencing gene expression and skin disease variant enrichment.
5 citations
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February 2022 in “Seminars in cell & developmental biology” This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.
211 citations
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April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
21 citations
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December 2006 in “Archives of dermatology” This abstract contains no research findings and pertains only to website navigation and policies.
54 citations
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November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.
40 citations
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January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
14 citations
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October 2018 in “Brain Research Bulletin” This article reviews the role of exosomes in promoting axonal regeneration and discusses recent findings on how exosome-borne molecules might influence the PTEN-mTOR pathway in injured neurons; it reports no new experimental results.
8 citations
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October 2023 in “Folia Histochemica et Cytobiologica” This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.
February 2022 in “Research Square (Research Square)” This study found that high TSPEAR expression in colorectal cancer was associated with poor prognosis and correlated with various tumor and immune-related factors.
6 citations
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August 1993 in “Archives of Dermatology” This study found that polymorphous light eruption (PLE) may include a wide range of conditions, requiring careful differentiation from similar skin disorders such as benign summer light eruption.