Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.

This case report describes a 31-year-old male who developed eosinophilic pleuropericardial effusion potentially linked to long-term valproic acid use, which resolved after adjusting his medication.

In this article, researchers describe a novel FUE device designed to enhance follicular unit excision surgery by minimizing follicular injury and improving ergonomics with features such as Bluetooth functionality, fingertip touch sensors, and automated operation.

AI-09 is safe, effective, and reduces wrinkles for up to 6 months.

This study found that skin wound healing was accelerated in young but delayed in older Med1(epi-/-) mice compared to wild-type mice, suggesting age-dependent roles of MED1 in epidermal regeneration.

This article provides an overview of Ebola virus disease, focusing on its impact on children and the limited understanding of their disease course, without reporting new clinical findings.

This study identifies a likely pathogenic homozygous missense variant in the AEBP1 gene in a patient with symptoms of classical Ehlers-Danlos syndrome, suggesting new perspectives for EDS classification and research.

In this animal study, exposure to 150 kHz electromagnetic radiation significantly reduced the number and size of follicular cysts in rats with estradiol valerate-induced polycystic ovaries.

This study found that ING5 knockout mice are prone to developing lymphomas and severe dermatitis, suggesting ING5 plays a role in tumor suppression and stem cell maintenance in vivo.

This study found that the K14 promoter exhibited higher activity in skin cell lines compared to other cell lines, while both K14 and K5 promoters were active in all tested cell lines.

This study reports differential gene expression in the leading edge and inner surface epithelial cells of murine eyelids, suggesting that distinct signaling pathways are active during embryonic eyelid closure.

This study found that the proteins Par3, mInsc, and Gαi3 cooperate to regulate LGN polarization and promote perpendicular cell divisions during murine epidermal morphogenesis.

In this study, Er:YAG laser therapy initially improved the appearance of eruptive vellus hair cysts but was ultimately ineffective due to early recurrence and concerns about atrophy or scarring.

In this study, transfection of the VEGF165 gene increased hair growth and rejuvenated the atrophic dermis in a mouse model of sclerotic skin.

This study suggests that eruptive vellus hair cysts often have atypical pathological changes and likely originate from the infrainfundibulum and sebaceous duct based on keratin expression analysis.

In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.

Electrical impedance spectroscopy improves biopsy accuracy and efficiency for skin lesions.

This research describes a two-step culture system for pluripotent mouse ES cells that produces hair follicle-like structures, providing a valuable model to study stem cell differentiation in vitro.

This study observed that ECMs produced by papillary fibroblasts showed the largest fibers and supported keratinocyte differentiation better than reticular fibroblast matrices, informing biomimetic material design for skin tissue engineering.

This study presents an improved protocol for isolating and culturing whole neonatal cochlear explants, enabling detailed analysis of hair cells and spiral ganglion neuron cells while simplifying culture steps without sacrificing explant quality, and was successfully tested on mice and rat cochleas.

This study found that VYC-15L (Juvéderm Volbella XC) was safe and effective for enhancing lip and perioral areas, achieving higher lip fullness improvement and fewer severe injection site reactions compared to NASHA, with effects lasting up to one year.

This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.

This summary reports that the 31st EADV Congress in Milan featured over 170 sessions with more than 600 speakers, offering dermatology and venereology professionals a platform to innovate practices and enhance patient care through global collaboration.

In a preclinical mouse model, this study found that early treatment with the selective SYK inhibitor entospletinib significantly improved survival rates and clinical outcomes for graft-versus-host disease after hematopoietic stem cell transplantation compared to placebo.

This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.

This review discusses human epidermal neural crest stem cells (hEPI-NCSC) as candidates for cell-based therapies and drug discovery but reports no new experimental results.

This study suggests that human embryonic stem cells may improve skin graft quality and functionality by enabling the identification and amplification of early ectodermal progenitors, pending confirmation from preclinical studies.

This study found that for anterior cervical discectomy fusion in patients with degenerative cervical disc disease, the PEEK cage resulted in greater pain reduction, while the dynamic cervical implant maintained a slightly better range of motion.

This study found that excess vitamin A induced stable glandular morphogenesis and mucous metaplasia in embryonic mouse vibrissa follicles, even after switching to standard medium.