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TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Certain drugs that block specific enzymes can help treat prostate diseases.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Flutamide reduces hair growth better but has more side effects.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Endocrine therapies for cancer significantly increase the risk of hair loss.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Sex hormones affect brain injury differently in males and females.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.