January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
182 citations,
August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
87 citations,
March 2005 in “Journal of Dermatological Science” Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
21 citations,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
2 citations,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
1 citations,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
June 2024 in “Research Square (Research Square)” Increased cell death and reduced cell growth in hair follicles contribute to baldness.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
80 citations,
June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
37 citations,
July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
7 citations,
September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
141 citations,
August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
87 citations,
July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
82 citations,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
158 citations,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
13 citations,
October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.
2 citations,
November 2007 in “Journal of Investigative Dermatology” Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
66 citations,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.