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Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Genetic variations affecting skin structure play a key role in severe acne.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Certain DNA variants can predict straight hair in Europeans but are not highly specific.

Two gene areas linked to male pattern baldness found, more research needed.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

No genetic link between prostaglandins and hair loss found.

Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

Most pediatric cancer patients in the study developed skin problems, often due to their cancer treatment.

Managing PCOS effectively requires focusing on psychological health, lifestyle changes, and medication.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

A woman developed thick gums from everolimus treatment after a kidney transplant.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

Common variants in the Trichohyalin gene are linked to straight hair in Europeans.

Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.

Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.