No Genetic Support for a Contribution of Prostaglandins to the Etiology of Androgenetic Alopecia

July 2013 in “ British Journal of Dermatology ”

Stefanie Heilmann, Dale R. Nyholt, Felix F. Brockschmidt, Axel M. Hillmer, Christoph Herold, Thomas Becker, Nicholas G. Martin, Markus M. Nöthen

TLDR No genetic link between prostaglandins and hair loss found.

The study found no genetic evidence to support the role of prostaglandins in the development of androgenetic alopecia (AGA), despite previous observations of differences in prostaglandin expression between balding and nonbalding hair follicles. The study was conducted by the MAAN consortium and was supported by the Life & Brain GmbH and the Alfried Krupp von Bohlen und Halbach-Stiftung.

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research Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases

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research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

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research Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness

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