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Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Targeting lipid metabolism can help treat advanced, resistant cancers.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.

MOF controls skin development by regulating genes for mitochondria and cilia.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Notch signaling disruptions can cause various skin diseases.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Pantethine may boost the immune system's ability to fight sarcoma.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.