97 citations,
September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
94 citations,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” EGF controls hair growth by regulating hair follicles' growth phases.
77 citations,
January 1980 in “Carcinogenesis” TPA is about 50 times more effective at promoting tumors than MZ.
39 citations,
January 2013 in “Journal of Investigative Dermatology” Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
36 citations,
September 1999 in “Toxicologic pathology” Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
28 citations,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
25 citations,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
24 citations,
January 2016 in “Lasers in Medical Science” Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.
23 citations,
July 2020 in “Aging Cell” Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
16 citations,
March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
10 citations,
February 2015 in “Clinics in Dermatology” The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
9 citations,
December 2013 in “Toxicological Research” Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
9 citations,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
4 citations,
January 2017 in “PubMed” Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
3 citations,
May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
1 citations,
February 2023 in “International Journal of Molecular Sciences” The fascial layer is a promising new target for wound healing treatments using biomaterials.
1 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Choosing the right method to separate skin layers is key for good skin cell research.
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.
The TAP flap is effective for treating armpit scars from burns, and tissue-engineered templates with hair follicles can help treat scalp burn alopecia.
205 citations,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
152 citations,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.