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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Genetics and hormones cause hair loss; finasteride treats it safely.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.

Long COVID causes various long-term health issues and needs better awareness and treatment.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

More research is needed to understand how testosterone is maintained in adult males.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Hair restoration for East Asians should consider their unique characteristics like head shape, hair thickness, and hair density, and use modified procedures and treatments to minimize scarring and maintain hair density.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Testosterone may influence COVID-19 severity and outcomes.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Iron deficiency anemia can cause itching, which often improves with iron supplements.

The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.