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11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

Some men don't respond to common hair loss treatments, but a new inhibitor, FOL-005, shows promise for targeting unwanted hair growth.

Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.

CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.

5-Alpha-Reductase inhibitors shorten COVID-19 recovery time in men.

Drugs that block GSK-3 show promise for treating various diseases.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.

Finasteride may help reduce impulsivity caused by pramipexole.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

JAK inhibitors show promise in effectively treating hair loss from alopecia areata.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.