January 2024 in “Journal of neurogastroenterology and motility” This study found that gQlab probiotics improved overall IBS symptoms, particularly in female and constipation-predominant patients, compared to placebo after 4 weeks of treatment.
57 citations
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December 2021 in “Nature Communications” In this study, enteroendocrine cells were shown to coordinate intestinal stem cell migration towards a wound in Drosophila by releasing a ligand that activates non-canonical Wnt signaling, aiding efficient tissue repair.
January 2023 in “Doria (University of Helsinki)” This study found that keratin 7 protein expression increased in colon cancer epithelial-derived cells when treated with neutrophil and macrophage conditioned media, suggesting immune cell-derived factors may influence keratin expression.
June 2026 in “World Journal of Gastrointestinal Pathophysiology” This review consolidates current knowledge about Cronkhite-Canada syndrome, highlighting its symptoms, diagnostic challenges, and evolving treatment strategies, but reports no new clinical results.
This study found that in vitro, EGCG may help treat colorectal cancer by targeting iron chelation and the ER stress pathway, leading to apoptosis in cancer cells while sparing normal cells.
June 1989 in “Diseases of the Colon & Rectum” Some patients experience temporary hair loss after ulcerative colitis surgery, likely due to illness rather than the surgery itself, and it usually grows back within six months.
2 citations
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May 2007 in “Pediatrics in Review” This case study reports a teenage boy with juvenile polyposis syndrome, presenting with microcytic anemia, growth failure, and rectal bleeding, leading to the diagnosis following colonoscopy and histologic examination of colonic polyps.
19 citations
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September 2006 in “Journal of Pediatric Gastroenterology and Nutrition” In this case study, a 12-year-old girl with severe Crohn colitis achieved impressive clinical and endoscopic remission after receiving infliximab and azathioprine as first-line treatment, suggesting potential benefits of early intensive therapy.
This study investigated the safety and efficacy of IV iron maltoside 1000 in treating iron-deficiency anemia among children with IBD and found a significant increase in hemoglobin levels by 6 weeks, maintained for up to a year, with minimal side effects reported.
1 citations
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June 2021 in “Case reports in gastrointestinal medicine” In this case study, a man's hair and nail symptoms, following dental treatments, resolved with mesalazine therapy after investigating suspected clindamycin allergy and diagnosing mucosal changes.
14 citations
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January 2015 in “Korean Journal of Pediatrics” This article reviews the importance of monitoring nutritional aspects like growth and anemia in pediatric inflammatory bowel disease, reporting no new research findings.
September 2021 in “Authorea (Authorea)” This case report describes a middle-aged Sudanese woman with intussusception associated with systemic lupus erythematosus (SLE), presenting with multiple symptoms including joint pain and abdominal issues.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
1 citations
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January 2014 This case study reports that telogen effluvium, a type of hair loss, was the initial symptom of Crohn's disease in a child, highlighting it as a rare extraintestinal manifestation.
7 citations
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November 2024 in “Journal of Inflammation Research” This review discusses the role of the TRPV4 channel in both normal and diseased intestinal functions and suggests that targeting TRPV4 may have clinical significance for treating intestinal diseases due to its involvement in intestinal barrier dysfunction.
October 2019 in “Journal of Evolution of Medical and Dental Sciences” This case report describes a 56-year-old male with chronic watery diarrhea, hyperpigmentation, and alopecia, in whom colonoscopy revealed multiple polypoidal lesions from the distal transverse colon to the rectum.
December 2019 in “The American Journal of Gastroenterology” In this study, three cases of Cronkhite-Canada syndrome revealed small bowel mucosal lesions, but these findings did not correlate with clinical symptoms or steroid treatment outcomes.
December 2013 in “Bőrgyógyászati és venerológiai szemle” This case report describes a 14-year-old boy who developed toxic epidermal necrolysis, involving over 30% of his body surface, following treatment with amoxicillin-clavulanate, cefuroxime, and lamotrigine.
January 2023 in “Open journal of pediatrics” In this case report, a 7-month-old girl with suspected acrodermatitis enteropathica and severe dermatitis experienced a tragic outcome despite zinc treatment, highlighting the challenges of diagnosing and managing this rare genetic disorder.
21 citations
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March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.
1 citations
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January 2014 in “PubMed” This case report describes a 10-year-old child experiencing telogen effluvium as the first symptom of Crohn's disease, highlighting it as a rare extraintestinal manifestation.
October 2021 in “VITEK Bidang Kedokteran Hewan” This case study reports on a 1-year-old male goat with various health issues including bloody stool, hair loss, and lice, treated with medication and supplements.
5 citations
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January 2020 in “Wiadomości lekarskie (Warsaw Poland)” This study found that patients with GERD and UCTD have significantly more frequent phenotypic and visceral markers than those with GERD alone, which should inform early diagnostic and treatment strategies.
10 citations
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January 2016 in “ACG Case Reports Journal” This case report describes a 73-year-old male with numerous colon polyps whose long-term use of Cape Aloe likely caused melanosis coli, which helped highlight the polyps' locations.
38 citations
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November 2020 in “International journal of biochemistry & cell biology” This review discusses the biological roles and diagnostic significance of keratins in mammalian colon epithelial cells and reports no new clinical results.
33 citations
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May 2018 in “Stem Cell Reports” This study demonstrates that Krt15 marks long-lived, multipotent, and injury-resistant crypt cells in the small intestine, which may serve as the cell of origin in intestinal cancer.
1 citations
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May 2025 in “Frontiers in Medicine” In this case series, dual-targeted therapy was observed to provide promising clinical responses in refractory inflammatory bowel disease, with 88.23% to 100% response rates across 9 months and an endoscopic response in 88.89% of evaluated patients, though some adverse events occurred.
January 2013 in “Open journal of gastroenterology” This case report describes a patient with ulcerative colitis who also presented with an atypical clinical aspect of lichen ruber planus, vitiligo, and alopecia areata.
October 2015 in “The American Journal of Gastroenterology” This case report observed a unique presentation of microscopic colitis with granulomatous inflammation in a patient whose symptoms resolved with budesonide treatment, suggesting a possible drug reaction, potentially linked to allopurinol.
September 2007 in “The American Journal of Gastroenterology” This case report describes a 37-year-old Filipino man with Cronkhite-Canada syndrome who improved after receiving nutritional support and medical treatment, despite the typically poor prognosis of the condition.