P095 The Very Interesting Small Bowel Lesions of Cronkhite-Canada Syndrome

    Akihito Tanaka, Shuji Kanmura, Kazuki Yutsudo, Yuga Komaki, Hiromichi Iwaya, Shiho Arima, Fumisato Sasaki, Shiroh Tanoue, Shinichi Hashimoto, Akio Ido
    TLDR Small bowel lesions in Cronkhite-Canada syndrome persist despite steroid treatment.
    The study examined small bowel lesions in 3 cases of Cronkhite-Canada syndrome (CCS) using capsule endoscopy. CCS is characterized by gastrointestinal polyposis and skin symptoms like hair loss and nail atrophy. The patients, aged 64, 65, and 75, presented with symptoms including diarrhea, skin pigmentation, and hair loss. Endoscopic findings revealed diffuse reddish, edematous mucosa, and villi abnormalities throughout the small bowel. All patients were diagnosed with CCS and treated with steroids, showing no relapse. The study concluded that small bowel lesions in CCS patients varied with the duration from onset to diagnosis, but were not linked to clinical symptoms or steroid response.
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