P095 The Very Interesting Small Bowel Lesions of Cronkhite-Canada Syndrome

    December 2019 in “ The American Journal of Gastroenterology ”
    Akihito Tanaka, Shuji Kanmura, Kazuki Yutsudo, Yuga Komaki, Hiromichi Iwaya, Shiho Arima, Fumisato Sasaki, Shiroh Tanoue, Shinichi Hashimoto, Akio Ido
    TLDR Small bowel lesions in Cronkhite-Canada syndrome persist despite steroid treatment.
    Cronkhite-Canada syndrome (CCS) is a non-hereditary disease marked by gastrointestinal polyposis and skin symptoms like hair loss, nail atrophy, and pigmentation. This study examined small intestine capsule endoscopy (CE) findings in 3 CCS cases. All patients, aged 64, 65, and 75, presented with symptoms including diarrhea, skin pigmentation, and hair loss. Endoscopic findings revealed diffuse reddish, edematous mucosa, and villi abnormalities throughout the small bowel. Despite treatment with steroids, the small bowel lesions persisted, indicating that the mucosal changes in the small intestine varied with the duration from onset to diagnosis.
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