19 citations
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June 2011 in “British Journal of Dermatology” Severe digestive issues in DRESS need early endoscopy for better treatment.
September 2023 in “Journal of the American Academy of Dermatology” Recognizing IPPP is crucial to prevent misdiagnosis and unnecessary treatments.
September 2010 in “Middle East Journal of Digestive Diseases” This case report highlights that treating ulcerative colitis with azathioprine and mesalamine led to hair regrowth in a middle-aged man with recent onset alopecia universalis, suggesting skin manifestations can be an extraintestinal indication of the disease.
9 citations
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June 2013 in “Australasian Journal of Dermatology” This case study reports on an adult with metastatic Crohn's disease treated with infliximab over 4.5 years, providing valuable follow-up data in this context.
February 2026 in “Immunity Inflammation and Disease” This study evaluated 386 patients with inborn errors of immunity and found that over half exhibited cutaneous, ocular, or hair manifestations, with bacterial skin infections and eczema being particularly prevalent. These findings may aid early diagnosis, especially in pediatric cases.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.
4 citations
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May 1989 in “Journal of the Royal Society of Medicine” Crohn's disease can cause hair loss before other symptoms appear.
October 2014 in “Transfusion Clinique et Biologique” This review discusses symptoms and syndromes associated with iron deficiency, with or without anemia, but reports no new clinical findings; the authors highlight the potential influence of intestinal factors on iron absorption.
October 2018 in “Exercise Biochemistry Review” In this mouse study, aerobic exercise was found to protect the intestinal mucosal barrier in obstructive jaundice by inhibiting the HMGB1 / TLR4 / NF-κB signaling pathway through the H2S / CSE system.
January 2018 in “Journal of Crohn s and Colitis” This study found that high-dose intravenous ferric carboxymaltose may reduce inflammatory activity in patients with inflammatory bowel disease and iron deficiency anaemia, as evidenced by decreased CRP levels and improved clinical disease indices.
August 2013 in “Gastroenterology” This case report highlights a 60-year-old patient's diagnosis with Cronkhite-Canada syndrome, characterized by gastrointestinal polyps, diarrhea, weight loss, brittle nails, alopecia, and skin changes, which showed improvement with treatment.
January 2016 in “Vojnosanitetski Pregled” Some treatments for inflammatory bowel disease can cause skin problems like rashes and melanoma.
This study found that OCT4B1 isoform expression was elevated in tissue and blood samples from patients with inflammatory bowel disease, suggesting a potential role in tissue repair.
27 citations
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February 2020 in “EMBO Reports” This study concluded that MEX3A is critical for maintaining Lgr5+ intestinal stem cells by regulating the PPARγ pathway, impacting intestinal homeostasis during postnatal development in mice.
January 1985 in “Japanese Journal of Clinical Immunology” This case report links bacterial endocarditis with aortic regurgitation in a patient with discoid lupus to tooth extraction and immunosuppressant therapy, noting recurrent enterococcus infections.
4 citations
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August 2023 in “Frontiers in Pediatrics” This study observed that children with multisystem inflammatory syndrome associated with COVID-19 exhibited physical intolerance and fatigue shortly after the acute phase, but significant improvements in exercise capacity, laboratory markers, and cardiac health were reported by six months post-discharge.
14 citations
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May 2017 in “Cell metabolism” This study found that glycolysis in Paneth cells provides lactate to support mitochondrial oxidative phosphorylation in intestinal stem cells, aiding their function and differentiation.
1 citations
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February 2025 in “Frontiers in Nutrition” This study found that a postbiotic derived from hawthorn and probiotics can alleviate loperamide-induced constipation in aged mice by regulating several physiological processes, including intestinal water and sodium metabolism, maintaining gut flora and barrier, reducing inflammation, and enhancing short-chain fatty acid metabolism.
October 2013 in “The American Journal of Gastroenterology” This case study highlights the importance of considering colorectal cancer as a potential diagnosis in young patients, especially females, with symptoms mimicking eating disorders, due to the risk of late-stage cancer discovery.
4 citations
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October 2022 in “Microbial Cell Factories” This study identified novel endophytic actinobacteria from the Citrullus colocynthis plant with antibacterial properties, suggesting potential for new antibiotic development against multi-drug-resistant bacteria.
October 2023 in “The American Journal of Gastroenterology” This case report describes chronic iron deficiency anemia in a patient with Cronkhite-Canada syndrome, highlighting the need for more data to guide treatment and cancer surveillance due to its rarity and mortality risk.
1 citations
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October 2010 in “Pediatrics in review” This review article discusses various pediatric malabsorption disorders, highlighting their symptoms, causes, diagnostic methods, and treatment but provides no new clinical results.
1 citations
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May 2015 in “Zeitschrift für Gastroenterologie” This study found a significant prevalence of autoimmune gastritis among iron deficiency patients, suggesting guidelines should include non-invasive testing for this condition during initial evaluations.
February 2018 in “The American Journal of Gastroenterology” This study observed that intravenous ferric carboxymaltose did not inhibit the drug-induced reduction of inflammatory activity in patients with inflammatory bowel disease, as indicated by lower CRP levels.
3 citations
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January 2011 in “Intestinal Research” This article reports on a patient case of Cronkhite-Canada syndrome, detailing symptoms and diagnostic findings, and reviews the syndrome's characteristics without presenting new clinical data.
January 2024 in “Journal of chemical health risks” In this study, gold nanoparticles-embedded ceria nanoparticles with enhanced antioxidant activities effectively reduced inflammation and colon injury in a colitis mouse model, suggesting their potential as a nano-therapeutic for inflammatory bowel disease.
8 citations
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June 2017 in “The Journal of Infection in Developing Countries”
53 citations
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May 1987 in “The Lancet” The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.
1 citations
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January 2015 in “The Journal of Dermatology” This letter to the editor presents a case of non-Herlitz junctional epidermolysis bullosa associated with a COL17A1 mutation and reports no new clinical findings.
October 2024 in “Dermatologica Sinica” This case report describes a 21-year-old male diagnosed with Crohn's disease and ulcerative pyoderma gangrenosum presenting with diverse extraintestinal symptoms, and highlights the success of a multi-drug treatment regimen including steroids and infliximab in improving clinical outcomes, though hematochezia was initially persistent.