A Case of Cronkhite-Canada Syndrome Presenting with Hematochezia

Cronkhite-Canada syndrome (CCS) was a rare, non-familial hamartomatous polyposis syndrome characterized by multiple polyps throughout the gastrointestinal tract, nail dystrophy, skin pigmentation, and systemic alopecia. A patient with CCS presented with hematochezia, melena, and a 1-month history of diarrhea, nail changes, taste disturbances, and alopecia. Diagnostic procedures, including upper endoscopy, colonoscopy, and capsule endoscopy, revealed numerous polyps in the stomach, small intestine, and large intestine. Histological analysis confirmed the diagnosis of CCS. The case highlighted the clinical presentation and diagnostic process of CCS, contributing to the understanding of this rare syndrome.