Unusual Cause of Chronic Diarrhea: Cronkhite-Canada Syndrome

    Manmeet Padda, Jenica Ryu, Nahid Molaie, Eric Olsen, Viktor Eysselein, David Chung, Binh V. Pham, Manmeet Padda, Jenica Ryu, Nahid Molaie, Eric Olsen, Viktor Eysselein, David Chung, Binh V. Pham
    Studysummary This case report describes a 37-year-old Filipino man with Cronkhite-Canada syndrome who improved after receiving nutritional support and medical treatment, despite the typically poor prognosis of the condition.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Cronkhite-Canada syndrome (CCS) was described as a rare, non-familial cause of multiple polyposis, characterized by symptoms such as diffuse gastrointestinal polyposis, alopecia, onchodystropy, and hyperpigmentation. A case study of a 37-year-old Filipino man highlighted these symptoms, including chronic diarrhea, weight loss, and alopecia, alongside laboratory findings of leukocytosis and vitamin deficiencies. Endoscopic examination revealed diffuse polypoid lesions, confirming the diagnosis. Treatment included nutritional support, medications, and vitamin supplementation, leading to gradual improvement. Despite treatment, the prognosis for CCS was poor, with a high mortality rate within five years of diagnosis.
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