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This study presents three spectrophotometric methods for determining finasteride in bulk and tablet forms, showing a linear relationship between absorbance and finasteride concentration.

This study found that torilin from Torilis japonica fruit extract inhibited 5 alpha-reductase in vitro more effectively than alpha-linolenic acid but less effectively than finasteride.

P-3074 effectively blocks scalp DHT better than oral finasteride.

Patients follow treatment well, but many change medicines; good information helps compliance.

This review highlights that bicalutamide, a non-steroidal antiandrogen used in prostate cancer treatment, is mainly effective through its (R)-enantiomer and emphasizes the need to monitor its adverse effects despite its targeted antiandrogenic action.

In this study, D-004 did not affect androgen-dependent development in rats exposed in utero, while finasteride caused significant changes in male offspring's androgen-dependent tissues.

This study found that prenatal exposure to finasteride in rats led to permanent changes in developmental endpoints like anogenital distance and nipple retention, which were predictive of further reproductive tract malformations.

In this study, researchers reported that while systemic antibiotics are often chosen first for treating severe folliculitis decalvans, they have a high discontinuation rate, suggesting an urgent need for more effective immunomodulatory treatments.

This study found that blocking the hypothalamic-pituitary-gonadal axis in male rats reduced baroreflex dysfunction and inflammation caused by endotoxemia, highlighting potential therapeutic benefits.

This study found that freeze-dried finasteride nanoparticles significantly improved the dissolution rate and pharmacokinetic parameters compared to pure drug formulations, suggesting enhanced stability and solubility for poorly water-soluble drugs.

This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.

This research paper reviews the anti-androgenic properties of the drug flutamide and its metabolite Sch 16423 but presents no new experimental results.

This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.

The researchers reported that oral finasteride 1 mg was associated with more frequent reports of sexual adverse events than dutasteride 0.5 mg, particularly after 2012, which may be influenced by the nocebo effect.

This study found that Epristeride and Finasteride reduced prostate development and testis weight in male rats, but only Finasteride appeared to impact reproductive function.

This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.

The article was retracted due to data integrity issues.

This case report found that a dog's progressive alopecia and prostatitis were caused by ingesting a transdermal estradiol cream, emphasizing the need to identify exogenous estrogen sources during evaluation.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

This study reports an improved and more cost-effective 7-step synthesis method for finasteride with an overall yield of 20.01%.

This study found that finasteride reduced opioid self-administration in zebrafish and rats without affecting pain relief, suggesting steroidogenic pathways may offer new treatment avenues for opioid use disorder.

Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.

This study found that oral administration of finasteride to pregnant rats caused dosage-related developmental toxicities, including hypospadias and decreased anogenital distance in male offspring.

This article describes the synthesis process of Finasteride from 3β-Hydroxypregn-5-en-20-one using a series of chemical reactions, including dehydrogenation and iodination.

This study developed and validated ultraviolet spectrophotometric and reversed phase high performance liquid chromatographic methods for simultaneously estimating Tamsulosin and Finasteride in tablet form, showing statistical validation and effectiveness in pharmaceutical analysis.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

In this study, researchers employed a modified coaxial electrospinning technique to create core-sheath nanofibers, which improved the transdermal delivery of finasteride compared to traditional monolithic nanofibers, showing enhanced penetration rates throughout the testing period.

This study found that a topical transethosomal system may enhance the skin penetration and deposition of naftifine compared to a marketed cream, potentially overcoming the stratum corneum barrier.