An Improved Synthesis of Finasteride from 4-Androsten-3,17-Dione

    December 2010 in “ Asian Journal of Research in Chemistry ”
    Nguyen Hai Nam, Ngo Anh Ngoc
    TLDR The new method makes finasteride cheaper and easier to produce.
    The document described an improved synthesis method for finasteride, a drug used to treat benign prostatic hyperplasia. The synthesis was achieved through a seven-step process starting from 4-androsten-3,17-dione, resulting in an overall yield of 20.01%. The improvements made the process less expensive and more commercially viable compared to previous methods reported in the literature.
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