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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Niosomes improve minoxidil skin delivery for hair loss treatment.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The Rotterdam Study aims to understand various diseases in older adults.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.