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The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Melatonin may help treat PCOS symptoms in rats.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

PCOS is a complex condition that can lead to serious health issues, but early diagnosis and treatment can reduce these risks.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

A new method accurately measures nine specific hormones in human blood.

Different types of PCOS need specific diagnosis methods and treatments.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

iNOS contributes to hair loss in obese diabetic mice and blocking it may encourage hair growth.

Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.