Polycystic Ovary Syndrome (PCOS)
January 2017
in “
Obstetrician & gynaecologist/The obstetrician & gynaecologist
”
polycystic ovary syndrome PCOS hyperandrogenism hirsutism alopecia insulin metabolism obesity anovulatory infertility clomifene citrate gonadotrophin therapy laparoscopic ovarian diathermy endometrial hyperplasia adenocarcinoma metabolic syndrome hair loss insulin resistance weight gain Clomid gonadotropin therapy ovarian drilling endometrial thickening cancer metabolic disorder
TLDR The document concludes that managing PCOS effectively requires considering ethnic differences, obesity's impact, and ethical concerns in treatment approaches.
Polycystic ovary syndrome (PCOS) presented symptoms such as menstrual cycle disturbances, hyperandrogenism (including hirsutism, acne, and alopecia), fertility issues, obesity, and psychological problems. Ethnic variations in insulin metabolism influenced the expression and treatment of PCOS. Obesity significantly impacted the syndrome's expression and management, especially concerning infertility. Management strategies for anovulatory infertility included lifestyle changes and ovulation-inducing therapies like clomifene citrate, gonadotrophin therapy, and laparoscopic ovarian diathermy. For those not seeking conception, managing menstrual issues involved preventing endometrial hyperplasia and adenocarcinoma and considering long-term metabolic risks. Ethical issues included the appropriateness of denying fertility treatment based on BMI, advising young women with polycystic ovaries about future risks, and screening relatives for PCOS or metabolic syndrome.
