January 2010 in “CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche)” This study found that combining metformin and clomifene citrate improved pregnancy outcomes and reduced miscarriage rates in women with PCOS and infertility undergoing intrauterine insemination.
41 citations
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April 1997 in “Fertility and sterility” In this case study, clomiphene citrate therapy restored hormonal balance and improved symptoms in a young male runner with hypogonadotropic hypogonadism related to endurance exercise.
29 citations
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April 2002 in “Human Reproduction” This study found an association between total ovarian volume, pre-antral follicle number, total follicular volume, and some biochemical indices of PCOS, but not with ovarian stromal volume.
3 citations
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January 2018 in “Journal of South Asian Federation of Obstetrics and Gynaecology” This study compared letrozole and clomiphene citrate for ovulation induction in women with polycystic ovary syndrome and found that while clomiphene led to more follicles, monofollicular development and endometrial thickness were higher with letrozole, and pregnancy rates did not significantly differ between the two treatments.
2 citations
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March 2017 in “Canadian Urological Association journal” This case report documents the first use of clomiphene citrate to potentially improve fertility in a man taking finasteride, highlighting sperm count issues associated with the medication.