Treatment With Metformin And Clomiphene Citrate In Women With Polycystic Ovary Syndrome And Infertility

    January 2010 in “ CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche) ”
    Luana Coco, S. Abbruzzo, Vincenzo Rapisarda, V. Santonocito, Tiziana Tomaselli, Giuseppe Zarbo
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    TLDR Metformin and clomiphene citrate together improve pregnancy chances and reduce miscarriages in women with PCOS.
    The study focused on women with polycystic ovary syndrome (PCOS), a condition affecting 5% of women and characterized by high androgen levels and anovulatory cycles, leading to symptoms like infertility, androgenic alopecia, and other skin conditions. It was found that a combined treatment of metformin and clomiphene citrate improved pregnancy outcomes and reduced miscarriage rates in women with PCOS undergoing intrauterine insemination.
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