Clomiphene Citrate Rescue of Spermatogenesis in Men with Infertility While Remaining on Finasteride: A Case Report

This case report discusses the use of clomiphene citrate (CC) to improve fertility in a 38-year-old male who was taking finasteride for androgenic alopecia and had azoospermia. The patient was started on CC therapy while remaining on finasteride, and after six months, his semen parameters improved, and his serum testosterone increased. This is the first documented case of semen parameters improving with the use of CC while the man remains on finasteride. The report suggests that there may be the possibility of improving semen parameters through the addition of CC, even if the patient continues to use finasteride to treat androgenic alopecia.