TLDR Clomiphene citrate improves fertility in men taking finasteride for hair loss.
This case report discusses the use of clomiphene citrate (CC) to improve fertility in a 38-year-old male who was taking finasteride for androgenic alopecia and had azoospermia. The patient was started on CC therapy while remaining on finasteride, and after six months, his semen parameters improved, and his serum testosterone increased. This is the first documented case of semen parameters improving with the use of CC while the man remains on finasteride. The report suggests that there may be the possibility of improving semen parameters through the addition of CC, even if the patient continues to use finasteride to treat androgenic alopecia.
54 citations,
September 2013 in “Fertility and Sterility” Finasteride can reduce fertility in some men, but stopping it increases sperm count.
36 citations,
February 2011 in “Fertility and Sterility” Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
38 citations,
December 2010 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
195 citations,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
211 citations,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively treats BPH, but needs more trials to understand potential.
195 citations,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
30 citations,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
