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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

Environmental pollutants can damage hair health and cause hair loss.

Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.

Lavender oil use in a child may be linked to early puberty signs and elevated tumor marker levels.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

The testes produce sperm and hormones essential for male development.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Some chemicals absorbed through the skin can cause serious health problems.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.

Finasteride may cause kidney damage.

New method effectively detects illegal hormones in anti-aging foods.

Glioblastoma cells can make androgens, which might help the tumor grow.

Frontal Fibrosing Alopecia needs better diagnostics and treatments, with dutasteride showing promise.