May 2026 in “Canadian Diabetes & Endocrinology Today” This review discusses the psychosocial impact and potential endocrine implications of androgenetic alopecia, particularly noting a moderate impairment in quality of life, but it reports no new clinical results.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the causes and management of premature greying in children, noting it may indicate underlying health issues, and emphasizes structured evaluations and treatments, particularly for nutritional deficiencies and hypothyroidism, to address hair depigmentation.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights concerns around premature greying in children, detailing possible links to nutritional deficiencies and other health issues, and emphasizes that structured evaluation and targeted treatment may aid in reversing the condition.
24 citations
,
February 2011 in “The American journal of pathology” This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.
4 citations
,
December 2021 in “Journal of clinical laboratory analysis” This study identified a splicing-site deletion in the DCAF17 gene associated with Woodhouse-Sakati syndrome in a large consanguineous pedigree, leading to typical phenotypic features.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review focuses on the clinical presentation and management challenges of menopausal acne and reports no new experimental findings.
December 2016 in “The European health psychologist” This study found that women with polycystic ovary syndrome often experience isolation, helplessness, resilience, and grief, suggesting a need for better support during diagnosis and treatment to improve wellbeing.
70 citations
,
February 2025 in “Journal of Ovarian Research” This review provides an analysis of the physiological and pathological aspects of polycystic ovary syndrome, emphasizing endocrine, metabolic, and inflammatory dimensions, but reports no new clinical results.
39 citations
,
November 1978 in “Annals of internal medicine” This brief report discusses spironolactone used as a treatment for hirsutism in a hyperandrogenic woman, offering no new clinical findings and focusing on its antiandrogenic properties.
3 citations
,
June 2024 in “Frontiers in Endocrinology” In this study, COC treatment led to greater improvements in sex hormone, endocrine factor, and metabolic levels among PCOS patients compared to those who did not receive the treatment.
2 citations
,
December 2024 in “Children” The authors of this review explore the link between thyroid disorders and skin conditions in children, highlighting how conditions like chronic urticaria, vitiligo, and alopecia may signal underlying thyroid issues and emphasizing the importance of early detection for timely diagnosis and personalized treatment.
2 citations
,
May 2023 in “Frontiers in Pharmacology” This review article summarizes findings that suggest natural products may help treat skin inflammation related to abnormal hormone secretion by the adrenal gland, as they can inhibit inflammation pathways and promote wound healing.
January 2022 in “IntechOpen eBooks” This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.
20 citations
,
July 2000 in “PubMed” This article describes an organized diagnostic approach for identifying nonscarring and scarring alopecias to aid family physicians in making accurate in-office diagnoses, but it reports no new clinical findings.
19 citations
,
January 1991 in “PubMed” This case study reported that glucocorticoid treatment markedly improved all clinical features in a girl with generalized komuragaeri disease, suggesting potential autoimmune involvement in the disease's pathogenesis.
15 citations
,
October 2019 in “BMJ Open” This protocol outlines a nationwide study to investigate the prevalence of metabolic and reproductive abnormalities, anxiety, and depression in Brazilian women with polycystic ovary syndrome, aiming to inform public health strategies.
8 citations
,
January 2018 in “Science of the total environment” This study found elevated levels of dioxin-like polychlorinated biphenyls in the fur of juvenile Australian fur seals with alopecia, suggesting a possible link to the syndrome and underscoring fur's utility for monitoring exposure.
2 citations
,
November 2015 in “Endocrinology, Diabetes & Metabolism Case Reports” This case report describes a 57-year-old man's late diagnosis of X-linked adrenoleukodystrophy, highlighting the need to consider this condition in patients with non-autoimmune primary adrenal insufficiency and neurological issues.
April 2026 in “Veterinary Medicine and Science” In this case report, authors described a pet golden hamster with a confirmed adrenocortical adenocarcinoma, where laboratory testing and diagnostic imaging enabled antemortem diagnosis, despite the species' rarity for these procedures.
March 2022 in “IntechOpen eBooks” This review discusses the complexities and co-morbidities associated with polycystic ovary syndrome, including its impact on metabolic and psychological health, and reports no new clinical results.
135 citations
,
April 2017 in “Advances in Clinical and Experimental Medicine” This review discusses the causes, clinical implications, and treatment options for polycystic ovary syndrome and reports no new results; the authors highlight both approved and emerging therapies.
49 citations
,
November 2022 in “Life” This review discusses global variations in polycystic ovary syndrome prevalence and highlights the need for more comprehensive studies to understand its association with race, ethnicity, and diagnosis criteria; it reports no new results.
37 citations
,
October 2024 in “JAMA Network Open” This study found that among reproductive-age women across India, there was a high prevalence of PCOS, with phenotype C being predominant and most women exhibiting metabolic abnormalities, highlighting the importance of integrating PCOS management into national health strategies.
35 citations
,
May 2023 in “International Journal of Preventive Medicine” This review discusses the various aspects of long COVID, highlighting its multi-organ impact, including symptoms like fatigue and dyspnea, and suggests that vaccination may play a role in prevention and management. Risk factors and potential therapeutic strategies are also examined.
35 citations
,
October 2017 in “JAMA dermatology” This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.
24 citations
,
January 2011 in “Sexual Development” This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.
20 citations
,
September 2015 in “Pediatric Annals” This article discusses the importance of recognizing polycystic ovary syndrome in adolescent girls during initial evaluations of menstrual irregularity and outlines current treatment strategies, reporting no new clinical results.
14 citations
,
September 2021 in “Journal of Inflammation Research” This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, may have higher rates of coexisting autoimmune diseases.
11 citations
,
October 2021 in “Orphanet journal of rare diseases” This study found that patients with RASopathies have lower serum IgA and CD8 levels compared to controls, indicating a potential risk for developing autoimmune disorders.
7 citations
,
May 2023 in “Nanomaterials” In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.