Practical Management of Hair Loss

    July 2000 in “ PubMed
    Jerry Shapiro, Marni C. Wiseman, Harvey Lui
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    TLDR The document outlines a method for diagnosing hair loss and suggests specific treatments based on the diagnosis.
    The document from 23 years ago provides an organized diagnostic approach for both nonscarring and scarring alopecias to help family physicians establish an accurate in-office diagnosis. The most common forms of nonscarring alopecias were androgenic alopecia, telogen effluvium, and alopecia areata, while scarring alopecia was caused by trauma, infections, discoid lupus erythematosus, or lichen planus. Key to establishing an accurate diagnosis was a detailed history, including medication use, systemic illnesses, endocrine dysfunction, hair-care practices, and family history. A 4-mm punch biopsy of the scalp was useful, particularly to diagnose scarring alopecias. Once a diagnosis had been established, specific therapy could be initiated. The evidence for therapeutic intervention for hair loss was quite strong at the time.
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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community My scalp punch biopsy results🤔?

      in Female  9 upvotes 1 year ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community I’ve read multiple times that Fin increases hair quality… NOT for me!

      in Treatment  97 upvotes 1 year ago
      A user has been on finasteride for 6 months and feels their hair quality has worsened, experiencing more hair loss and scalp irritation. They are considering seeing a dermatologist, while others suggest the issue might be unrelated to finasteride, possibly due to deficiencies or other conditions.

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