January 2024 in “International Research Journal of Modernization in Engineering Technology and Science” This review suggests that combining nanotechnology with herbal components in hair cosmetics may improve the delivery and effectiveness of treatments for issues like damage, dandruff, and hair loss.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
48 citations
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December 2013 in “Drug Delivery and Translational Research” This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.
44 citations
,
August 2017 in “Food Bioscience” This study found that betasitosterol-loaded nanostructured lipid carriers, when added to butter, improved its nutritional profile and antioxidant properties, maintaining stability over a three-month storage period.
16 citations
,
September 2018 in “Journal of Ethnopharmacology” This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.
3 citations
,
August 2013 in “Tropical Journal of Pharmaceutical Research” This study concluded that the Box-Behnken experimental design effectively optimizes the size of finasteride nano-emulsions by assessing the impact of various experimental factors.
June 2026 in “Journal of Pakistan Association of Dermatologists” This study reported that the development of nanoemulsion-based hair growth serums is increasing, with enhanced international collaboration and scientific presence, especially between China and the United States.
39 citations
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April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
November 2025 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, researchers developed and tested hair gels using pectin from mango and coconut oil as a potential natural treatment for traction alopecia in black women, reporting stability in some formulations and rheological properties that may support their use in innovative phytocosmetics.
4 citations
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May 2007 in “Journal of Dispersion Science and Technology” This study found that hinokitiol in cationic vesicles promoted hair growth in mice, potentially due to its high substantivity on the skin.
January 2026 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, researchers developed mango pectin-based hair gels for traction alopecia in black women, finding the gels exhibited beneficial properties for hair and good stability, suggesting potential as phytocosmetic treatments without common adverse effects.
2 citations
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November 2024 in “AAPS PharmSciTech” In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.
2 citations
,
February 2023 in “Research Square (Research Square)” In this study, a newly engineered scaffold, PADM-MX-Ag-Si@Dox, demonstrated potential as a multifunctional biomaterial for postoperative melanoma treatment by controlling drug release, enhancing wound healing, and enabling real-time tumor surveillance through temperature, pH, and electrical stimuli.
November 2025 in “Discover Pharmaceutical Sciences” In this study, a nanoemulsion containing lavender, peppermint, and rosemary essential oils was developed and shown to promote hair growth in mice at a rate comparable to 2% topical minoxidil, suggesting a promising natural alternative due to its antioxidant and anti-inflammatory effects.
4 citations
,
January 2022 in “Current pharmaceutical design” This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
67 citations
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January 2022 in “Theranostics” This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.
28 citations
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September 2019 in “International Journal of Nanomedicine” This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.
11 citations
,
June 2023 in “Drug Delivery and Translational Research” In this study, researchers developed and tested a gel containing apocynin-loaded nanoparticles that showed promising results in treating rheumatoid arthritis in rats, suggesting potential for novel topical treatments in inflammatory conditions.
2 citations
,
August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
August 2025 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion-based hair serum containing M. oleifera seed oil, which maintained its physical characteristics and reduced the oil's sticky texture, making it more suitable for hair loss treatment compared to traditional formulations.
June 2026 in “International Journal of Drug Delivery Technology” This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.
April 2026 in “International Journal of Drug Delivery Technology” This study discusses advancements in nanotechnology and theranostic dressings, which may significantly improve chronic wound care by effectively targeting biofilms and enabling real-time monitoring, although obstacles to broad applicability and sustainability remain.
1 citations
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January 2024 in “Journal of applied pharmaceutical science” This study investigated bacterial isolates from Xylocarpus sp. mangrove fruit and found that these symbiotic bacteria exhibit antibacterial, antifungal, and hair follicle growth properties, suggesting potential applications in the cosmetic bioindustry, particularly for treating alopecia.
52 citations
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January 2020 in “Scientific Reports” This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.
19 citations
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December 2013 in “European journal of pharmaceutics and biopharmaceutics” This study found that encapsulated Garcinia mangostana Linn extract in a cream base penetrated more deeply and homogeneously into porcine ear skin compared to other formulations.
130 citations
,
August 2020 in “Drug Design Development and Therapy” This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.
2 citations
,
January 2018 in “Elsevier eBooks” This review discusses the use of lipid nanoparticles for topical and transdermal delivery of pharmaceuticals and cosmeceuticals and reports no new clinical results.
January 2026 in “Nanoscale Advances” This review provides an overview of microneedle-assisted photomedicine, detailing diagnostic and therapeutic strategies, design principles, and challenges for translating this approach to skin disease management.
March 2025 in “Scientific Reports” This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.