29 citations
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September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
3 citations
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January 1984 80 citations
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August 2022 in “Materials Today Bio” This study developed a double-network hydrogel using polyacrylamide and catechol-chitosan to enhance mechanical properties and promote drug release, aiding in inflammation regulation and wound healing for chronic wounds with challenging microenvironments.
297 citations
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December 2005 in “Journal of controlled release” This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.
10 citations
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January 2013 in “International Journal of Research in Pharmaceutical Sciences” This study found that a microemulsion containing extracts of Hibiscus rosa sinensis and Murraya koenigii was non-irritating and more effective at controlling hair loss than a standard marketed formulation.
2 citations
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October 2022 in “Journal of Sustainable Materials Processing and Management” This research found that Nano-Transfersomes containing Vitamin E and aloe vera showed improved permeability and prolonged drug release compared to a marketed formulation, with no skin irritancy observed in mice, potentially offering a sustainable and biocompatible option for psoriasis management.
56 citations
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September 2016 in “Pharmaceutical Research” This study found that imiquimod combined with fish oil in a bigel formulation enhanced antitumor effects and reduced inflammatory side effects in a skin cancer model.
This study evaluated amphiphilic self-assembling peptides as drug delivery systems and found they effectively ensured prolonged release and therapeutic efficacy for timolol in glaucoma and for chemotherapy agents in cancer treatment, with significant tumor size reduction observed in animal models.
2 citations
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January 2024 in “Pharmaceuticals” This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.
9 citations
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January 2017 in “Organic Process Research & Development” This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.
June 2022 in “Farmacevtičnij časopis” This study developed a technology for a combined gel named "Biosedum Plus" intended for treating and preventing radiation skin damage, detailing its formulation and critical processing parameters.
60 citations
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December 2013 in “PLoS ONE” The researchers found that inhibiting soluble epoxide hydrolase, either genetically or pharmacologically, delayed the onset of chemically induced seizures related to GABA antagonism in experimental models.
April 2025 in “BMC Chemistry” This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
April 2026 in “Lithuanian University of Health Sciences” In this study, cinnamic acid in solution form showed strong antifungal activity against Microsporum canis, but when incorporated into hydrogels, the acid's diffusion and resulting antifungal performance decreased, though it maintained effectiveness for potential prolonged exposure.
7 citations
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January 1976 in “International Journal of Environmental Studies” This study found that applying a mix of cholesterol and Tween 60 detergent to mouse skin significantly reduced epidermal cell mitotic activity.
43 citations
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July 1994 in “Journal of Cell Science” This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.
1 citations
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April 2022 in “Applied sciences” This study reports the development of a microemulsion using Momordica charantia extract, which demonstrated strong antioxidant and 5α-reductase inhibitory activity, potentially aiding hair loss management. The microemulsion was stable over 12 weeks, suggesting its future potential for cosmetic or pharmacological applications.
In this experimental study, mixing temperature and rate were found to significantly influence cream's physical properties, with mixing rate affecting spreadability and temperature affecting viscosity.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.
June 2024 in “International Journal of Cosmetic Science” This study found that various plant oils can penetrate the lipid-rich cell membrane complex of hair, improving its fatigue strength by preventing flaw propagation, with greater penetration observed for oils containing shorter chain lengths and unsaturated fatty acids.
October 2023 in “Materials chemistry and physics (Print)” Adding keratin to a mix of cow hair and plant-based plastic makes it stronger.
2 citations
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January 2019 in “Recent Advances in Biology and Medicine” This study found that a combination of 5% DMSO and BSA minimizes toxic effects on the cytogenetic stability of dermal papilla cells during cryopreservation.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effectiveness of three formulated hair conditioners—Herbal, Synthetic, and Ayurvedic—using organoleptic and physicochemical tests like pH, Dirt Dispersion, and Stability, with the main aim to develop a product that meets user compliance and desired hair care effects.
1 citations
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October 2025 in “Beni-Suef University Journal of Basic and Applied Sciences” This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.
49 citations
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April 2003 in “Biomaterials” In this study, BS and BO combined showed a synergistic effect in enhancing wound healing in rat skin lesions compared to using either alone or Flamazine®.
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.
August 2025 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion-based hair serum containing M. oleifera seed oil, which maintained its physical characteristics and reduced the oil's sticky texture, making it more suitable for hair loss treatment compared to traditional formulations.
July 2026 in “International Journal of Multidisciplinary Sciences and Arts” In this study, researchers formulated a pomade using papaya seed oil and virgin coconut oil at various concentrations and found it to be stable, non-irritating, and preferred by users, with the 7.5% concentration being most favored for providing shiny and moisturized hair.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.