Transglutaminase-Mediated Cross-Linking in Mammalian Epidermis
January 1984
Research cited in this study
8 / 8 resultsresearch The Origin of Citrulline-Containing Proteins in the Hair Follicle and the Chemical Nature of Trichohyalin, an Intracellular Precursor
research Human Epidermal Transglutaminase: Preparation and Properties
This study purified a transglutaminase enzyme from human epidermis that requires calcium or strontium for activity and forms cross-linked polymers, but its detailed activation mechanism remains unclear.
research Vertebral Epidermal Transamidases
Transamidases are present in the epidermis but their exact role is unclear.
research Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles
This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.
research Kinetic Studies With Transglutaminases
This research found that the transfer reaction catalyzed by human plasma and guinea pig hair follicle transglutaminases aligns with a ping-pong mechanism involving peptide-bound glutamine.
research Transglutaminase from Hair Follicle of Guinea Pig
This study found that a unique transglutaminase in guinea pig hair-follicles, distinct from liver transglutaminase, likely plays a role in forming protein cross-links via ε(γ-glutamyl)lysine bonds.
research The Occurrence of the ε-(γ-Glutamyl)Lysine Cross-Link in the Medulla of Hair and Quill
research Iε-(γ-Glutamyl) Lysine Cross-Linkage in Citrulline-Containing Protein Fractions From Hair
Specific cross-linkages help make hair proteins stable and strong.
Related Research
5 / 5 resultsresearch Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1
research Hair Follicle-Specific Keratins And Their Diseases
This review discusses hair keratins and hair follicle-specific epithelial keratins and their association with inherited hair disorders, reporting no new clinical results.
research Keratins of the Human Hair Follicle
More research is needed to understand how hair keratins work and their role in hair disorders.
research Hair Follicle Differentiation And Regulation
This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
In this study, in vitro growth of human hair follicles did not alter hair keratin expression patterns, maintaining follicle integrity and proper keratinization similar to in vivo conditions.