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Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Loss of TET2 increases the risk of skin and oral cancer.

A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.

Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.

SOX9 is essential for the development of various organs and hair follicles.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Hair follicle stem cells have significant potential for treating various disorders.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Ephrins slow down skin and hair follicle cell growth.