61 citations
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June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that light stimulation of intrinsically photosensitive retinal ganglion cells in the eyes can activate hair follicle stem cells through a neural circuit involving the sympathetic nervous system.
August 2026 in “npj Flexible Electronics” This review outlines the potential of soft bioelectronics in wound care, emphasizing their ability to monitor and manage wounds through integrated smart systems and identifying challenges for future advancements in the field.
8 citations
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June 2025 in “Stem Cell Research & Therapy” This review discusses the potential of exosome therapy for treating diabetic peripheral neuropathy but highlights the need for more robust preclinical trials before clinical application.
February 2026 in “Bioengineering” This study indicates that while EV-based therapies are advancing towards clinical use in regenerative medicine, addressing methodological and regulatory hurdles is essential to fully harness their therapeutic potential.
3 citations
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November 2022 in “International journal of molecular sciences” This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.
20 citations
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September 2019 in “Nanomaterials” This study developed a portable electrospinning device that mimics hair for cosmetic thickening in a mouse model, showing performance comparable to benchtop models with added safety and cost benefits.
27 citations
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August 2015 in “Experimental Dermatology” In this study, electrical stimuli at low voltage and frequency settings promoted hair growth in vitro and in rabbit models, possibly by activating pathways like Wnt/β-catenin.
7 citations
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January 2020 in “International Journal of Molecular Sciences” This study found that exposure to extremely low-frequency electromagnetic fields at specific intensities significantly enhanced human hair follicle cell activation and proliferation, suggesting a potential new treatment approach for alopecia.
5 citations
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July 2022 in “Frontiers in Medicine” In this study, the combination of ECM-C with microneedle and radiofrequency treatments improved periorbital wrinkles, skin elasticity, and thickness more effectively than ECM-C with microneedles alone, but subjective evaluations showed no significant differences.
October 2024 in “Irish Journal of Medical Science (1971 -)” In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.
December 2024 in “Advanced Composites and Hybrid Materials” This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.
10 citations
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February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” This study found that local synthesis of 17β-estradiol and 5α-dihydrotestosterone, combined with specific stimulation patterns, is crucial in determining the direction and strength of long-term synaptic effects in the hippocampal CA1 region of male rat slices.
1 citations
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February 2026 in “ACS Omega” This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.
11 citations
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July 2015 in “Journal of Anatomy” This review summarizes a 15-year collaboration on the role of synaptic-like vesicles in mechanosensory nerve terminals and suggests potential therapeutic implications for conditions like hypertension and muscle spasticity.
March 2026 in “Materials Today Chemistry” Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.
July 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” In a pilot study with 21 patients, the niostem device increased hair counts and density and enhanced testers’ self-perception of hair growth at 6 months without reported adverse effects, suggesting potential benefits for androgenetic alopecia.
2 citations
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October 2016 in “European Neuropsychopharmacology” 4 citations
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January 2026 in “Micro” This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.
4 citations
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March 2019 in “Experimental Biology and Medicine” This study found that exposure to 50 Hz electromagnetic fields enhanced hair regrowth in mice by increasing stem cell proliferation and keratinocyte growth factor expression, suggesting potential benefits for hair loss treatment.
June 2026 in “Facial Plastic Surgery Clinics of North America” 19 citations
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April 2021 in “Stem Cell Research & Therapy” This study found that transplantation of autologous stromal vascular fraction cells increased skin thickness and improved regeneration when combined with mechanical stretching, without severe adverse events.
1 citations
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December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
January 2005 in “Di-san junyi daxue xuebao” This study found that treatment with aerosol bioelectricity accelerated wound healing in burned rats by enhancing the expression of EGF and β_1 integrin in skin basal and hair follicle cells.
1 citations
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September 2021 in “Physiology News” The abstract contains only graphic design specifications and reports no new research findings.
1 citations
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December 2018 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study found that combining electrotherapy with aromatherapy led to increased hair shaft thickness in men with androgenetic alopecia, although no changes in the scalp were observed.
1 citations
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August 2016 in “Journal of nature and science” This study observed light flashes and repulsion effects in a single-slide preparation of human hair with a special solution, suggesting potential electromagnetic field emissions from the hair.
October 2021 in “Journal of Investigative Dermatology” In this research, investigators used in vitro models to study the Merkel cell-neurite complex and reported that mechanical stimulation, similar to gentle touch, can induce molecular changes that are potentially relevant to hair growth, thus contributing to the understanding of its underlying mechanisms.
1 citations
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July 2024 in “Nanomedicine” This study demonstrated that EVs from pluripotent stem cell-derived mesenchymal stem cells improved recovery and function in ischemic lower limbs by enhancing angiogenesis through the ERK/MAPK signaling pathway.
5 citations
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July 1999 in “Journal of Anatomy” This study observed that methylene blue staining and zinc iodide-osmium tetroxide techniques effectively revealed anatomical details of intraepidermal nerve fibre endings in the rat's mystacial pad, suggesting their potential role in mechanoreception.
July 2026 in “Regenerative Medicine” In this study, a dual-layer electrospun nanofibrous mat incorporating chitosan nanoparticles, growth factors, and hair follicle bulge stem cells significantly enhanced wound healing in a rat model.