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This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.

This study found that the protein Fetuin A, when injected into fetal wounds that typically heal without scarring, caused scar formation and increased collagen production in fibroblasts in an animal model.

In this study, injecting Fetuin A into embryonic mouse wounds led to scar formation, suggesting the protein may play a role in scar development by promoting collagen production.

This study observed that, contrary to common belief, aged Balb/C mice showed better wound healing than younger mice despite greater weight loss, possibly due to increased T regulatory cells.

Men and women need different facial rejuvenation treatments due to distinct aging processes and anatomical differences.

This review explores the role of advanced glycation end products in skin aging and their interaction with oxidative stress, but reports no new clinical findings.

This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.

This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.

This article reviews the skin and hair changes associated with menopause due to hormonal shifts and reports no new clinical results.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

EF and PXE not closely related.

This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This review discusses current concepts in wound repair and suggests that these evolving paradigms might also explain regenerative processes in various organ systems, but it reports no new research findings.

This review discusses the potential of stem cell secretome in regenerative medicine and suggests that its paracrine effects, rather than direct cell replacement, may drive therapeutic benefits.

This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.

This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.

In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.

This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

This review explores recent advances in understanding molecular mechanisms of tissue regeneration in mammals and suggests potential therapeutic targets, but it reports no new clinical results.