Antiglycants

The document from 2017 explored the role of advanced glycation end products (AGEs) in skin aging and the potential of anti-glycation treatments. AGEs, which accumulate in the skin due to factors like UV exposure and lifestyle choices, contribute to skin aging by reducing collagen, increasing stiffness, and impairing cellular functions. The document highlighted that AGEs are more prevalent in diabetic skin and that the body's capacity to remove AGEs can be overwhelmed by poor lifestyle choices. Anti-glycation strategies, such as those used in diabetes treatment, could potentially be applied to skin aging, but evidence for their effectiveness is limited. The document also mentioned the use of skin autofluorescence to evaluate anti-aging products and cited a study with ten postmenopausal females that showed the anti-glycation ability of pomegranate extract. Other compounds like carnosine and niacinamide were also noted for their potential skin health benefits. However, the document concluded that more research is needed to support the use of anti-glycants in reducing the rate of aging, with a focus on preventing AGE formation.