Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.

The LTF gene may help predict and manage nonspecific orbital inflammation.

In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.

This study found that nuclear androgen receptor expression was enhanced by dihydrotestosterone in rat gubernacular mesenchyme, but this did not affect muscle morphology or matrix composition during fetal development.

In this study, transgenic mice expressing a truncated form of latent transforming growth factor-β-binding protein exhibited altered hair cycles due to increased active transforming growth factor-β, impacting keratinocyte proliferation and hair cycle phases.

In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.

This study observed that tissue-engineered skin, using VEGF165 gene-modified cells embedded in astragalus polysaccharide-containing 3D printed scaffolds, enhanced early vascularization, and collagen and hair follicle regeneration, leading to improved skin repair in nude mice with full skin defects.

This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.

This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.

This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.

This review explores the role of nanotechnology in wound healing, highlighting its potential through antimicrobial properties, selective inflammatory action, angiogenesis promotion, and its use in drug and gene delivery.

In this study, adenosine was found to stimulate hair follicle growth in vitro by promoting growth factor expression, β-catenin activation, and downstream signaling pathways.

This review examines the potential of K18 as a diagnostic and prognostic marker in epithelial-derived tumors, highlighting its specific expression in tumor tissues and interaction with proteins involved in tumor progression, without reporting new clinical findings.

In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.

This study reports that short exposure to vibration causes epithelial cells to retract filopodia, concentrate actin at their edges, and increase expression of the protease calpain, suggesting a mechanism for vibration-induced pain relief.

This study investigated the effects of 10600nm CO2 dot laser and Nd: YAG laser on Wistar rats' skin, finding that CO2 laser treatment resulted in higher positive expression of MMP-1 and TIMP-1 compared to Nd: YAG laser, with statistically significant differences noted.

This study found that treating skin wounds with a combination of epidermis-derived epithelial-like stem/progenitor cells and platelet-rich plasma improved tissue repair and increased vascularization and elastin content compared to platelet-rich plasma alone.

This review discusses the fundamental hallmarks of aging as they relate to skin aging and highlights the prominent roles of oxidative damage and the extracellular matrix in photoaging, reporting no new results.

This review discusses the multiple factors contributing to skin aging, including cellular changes and environmental influences, and highlights its recognition as a disease with significant implications beyond cosmetic concerns, without reporting new research results.

This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.

This study found that applying a topical inhibitor of TGF-β1 may enhance scar maturation and improve the appearance of hypertrophic scars in a nude mouse model after two weeks.

This study found no qualitative skin differences during development between mutant hairless USP mice and BALB/c mice, except for enlarged cysts in the hairless strain.

This review found limited but suggestive evidence that Calcium Hydroxylapatite may promote skin regeneration through increased collagen production, cell proliferation, and angiogenesis, although most studies had methodological limitations.

This review highlights the potential of ellagic acid for treating various skin conditions due to its antioxidant, anti-inflammatory, and depigmenting properties, but notes that novel formulations are needed to overcome its poor solubility and skin permeability to enhance clinical efficacy.

This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.

This review addresses the limitations of current engineered skin substitutes for burn patients and highlights potential improvements through stem cell biology and skin morphogenesis, but it reports no new clinical results.

This pilot study suggests that topical PRP may improve facial rejuvenation, with observed enhancements in collagen production and skin architecture over 8 weeks.

The researchers reported that marine-derived saccharides, specifically L-fucose and chondroitin sulphate disaccharide, supported skin and hair health by promoting cellular proliferation, enhancing extracellular matrix production, and aiding the hair cycle's growth phase, potentially minimizing aging effects.

This review synthesizes current advances in transcriptomics and RNA regulatory networks, alongside stem cell-derived skin organoid research, to propose a conceptual framework for understanding and potentially guiding regenerative skin repair, without claiming clinical readiness.

This review examined and discussed the role of dermis-derived factors in the regulation of melanogenesis, noting their significance in both normal and abnormal mammalian skin conditions, suggesting an underexplored area of study compared to dermal and epidermal influences.