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This study found that chronic administration of dutasteride in rats did not affect spermatogenesis or oxidative stress in the testes, although it altered hormone levels.

In this case report, a patient with pseudovaginal perineoscrotal hypospadias due to 5α-reductase deficiency presented gender dysphoria, and after genomic sequencing confirmation, injectable testosterone undecanoate treatment successfully developed desired male secondary sexual characteristics.

This research found that Leydig cells significantly rely on synthesizing omega-6 HUFAs to support male steroid hormone production, highlighting a new role for these fatty acids in the male reproductive system.

This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.

This study found that combining longxuejie and finasteride effectively reduced intra-operative bleeding during TURP without side effects compared to finasteride, longxuejie alone, or control.

This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.

This study found that free testosterone levels were 29% higher with the levonorgestrel implant than with the DMPA injection, which may impact sexual function, mood, and side effects like acne.

This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.

This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.

In this study, daily administration of 100mg DHEA for 16 weeks in women with adequate ovarian reserve did not modify metabolic or reproductive variables, apart from increased antral follicular count and anti-Müllerian hormone levels.

This study discusses how testosterone exerts its effects directly or through conversion to metabolites, DHT and estradiol 17β, each influencing different physiological processes, noting that DHT conversion is necessary for certain effects but not for muscle, bone, or erythropoiesis impacts.

In this study, the authors concluded that COVID-19 may not cause direct long-term harm to testicular function, but temporary indirect effects could occur, suggesting a possible delay in pursuing parenthood post-recovery.

This review suggests that oocyte retrieval may be viable for transgender men on testosterone therapy, with potentially manageable effects on fertility preservation without requiring extensive hormone suspension.

This study suggests that the regulation of GABA‐A δ subunit expression by ovarian progesterone-derived neurosteroids may influence seizure susceptibility in catamenial epilepsy.

This article discusses the causes and consequences of hyperestrogenism in men of reproductive age and emphasizes the need for proper hormonal testing and treatment, reporting no new clinical findings.

Finasteride may help reduce tic severity in male Tourette syndrome patients.

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

This study presents a new survey instrument that was cognitively tested for understanding menstrual cycle characteristics and androgen excess, including hirsutism, alopecia, and acne.

This study developed and validated a mass spectrometric method to measure hydroxy-androgens in serum, which aids in understanding androgen synthesis in castration resistant prostate cancer.

This study found that a 3 mm margin around the prostate CTV may be adequate if accompanied by frequent imaging, but superior-inferior displacements were notably greater than in other directions.

This study highlights that shock wave therapy for erectile dysfunction is commonly performed by nonurologists in major U.S. metropolitan areas, with high costs and varied treatment protocols.

This article reviews guidelines and medications for treating benign prostatic hyperplasia but presents no new clinical results.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

This study found that intracrine androgen signaling via 5α-reductase is essential for optimal endometrial decidualization and vascular development during this process in mice.

This review clarifies what constitutes an emollient and explains that both cosmetic and pharmaceutical emollients share the same functions, reporting no new research findings.

This paper introduces a framework attributing Post-SSRI, Post-Finasteride, Post-Retinoid, and an unnamed sexual dysfunction syndrome to downregulated estrogen receptor activity, potentially guiding future treatments in sexual medicine.

This study suggests that combining LMWHA solution and HCO might improve mild to moderate urinary incontinence in women with GSM, potentially offering benefits over HA therapy alone, but further research is needed.