74 citations
,
July 1991 in “The Journal of Urology” This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.
229 citations
,
March 2001 in “European journal of endocrinology” This review discusses the complex relationship between testosterone levels and male appearance and behavior, emphasizing the limitations and potential biases in making generalizations from current data.
33 citations
,
September 2006 in “International Journal of Cosmetic Science” This study found that applying caffeine significantly improved the skin barrier function of male volunteers by reducing transepidermal water loss compared to female volunteers.
February 2023 in “Sexual Medicine Reviews” This review explores the potential of topical minoxidil as a treatment for erectile dysfunction, indicating that while a mild erectile response was observed, evidence remains insufficient for confirmation.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
6 citations
,
September 2020 in “Journal of Mind and Medical Sciences” This study found that vaginal surgical interventions for genital prolapse or urinary incontinence did not significantly alter the quality of sexual life in women, with a portion reporting improvement and others experiencing no change or decreased libido.
June 2026 in “European Medical Journal” This study found that among male and female patients at a dermatology clinic, higher severity of androgenetic alopecia was statistically associated with lower sexual function scores, although the findings should be interpreted cautiously due to sample size and methodological limitations.
21 citations
,
December 2015 in “Development Growth & Differentiation” This study introduces genital sex differentiation parameters (GSDP) to analyze sexual differences in external genitalia and perineum development in mice, revealing varied sensitivity to androgen inhibition in genital structures.
In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.
163 citations
,
November 1976 in “Annals of Internal Medicine” This study found that adults with sickle cell anemia exhibited androgen deficiency due to primary testicular failure, and there was a significant correlation between erythrocyte zinc levels and serum testosterone.
March 2018 in “European Urology Supplements” Patients follow treatment well, but many change medicines; good information helps compliance.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, Dodatek A operationalizes the Functional Androgen Axis framework by defining three system-level indices and an efficiency metric to describe androgen function, incorporating key methodological improvements and acknowledging significant limitations for future empirical validation.
October 1988 in “Pediatric research” In this study, researchers observed that the sequence of maturity markers in normal boys showed specific time lags, with some markers appearing before and others after spermarche.
186 citations
,
February 2015 in “Frontiers in Neuroscience” This review discusses the complex effects of testosterone on the brain, emphasizing sex differences, and reports no clinical results; the authors highlight the inconsistencies in current study findings.
9 citations
,
April 1985 in “Canadian Journal of Zoology” This study investigated the interdigital glands of moose, detailing their unique green hair coloration and the function of sebaceous and sweat glands, particularly during the rut period.
September 2010 in “Zhonghua miniao waike zazhi” This study found that long-term administration of tamsulosin hydrochloride 0.2 mg is effective, safe, and well-tolerated for improving symptoms and quality of life in patients with LUTS of BPH.
98 citations
,
September 1981 in “Fertility and Sterility” 1 citations
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January 2015 in “Sexual Medicine Reviews” This review discusses the management of recurrent ischemic priapism, highlighting that various treatments show differing efficacy and side effect profiles but that more research is needed to refine these strategies.
14 citations
,
March 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the flexibility and diversity of tissue stem cell systems, particularly focusing on the motility and ligand distribution of spermatogenic stem cells, without presenting new experimental results.
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” This collection of articles in AOGS includes findings on tetranectin as a possible prognostic marker for advanced ovarian cancer, and the effectiveness of tension-free vaginal tape for recurrent stress urinary incontinence.
43 citations
,
April 2011 in “AJP Endocrinology and Metabolism” This study found that androgens increase Odc1 expression in skeletal muscle myoblasts, promoting proliferation and delaying differentiation.
21 citations
,
October 2015 in “Current Drug Targets” This review discusses the comparative efficacy of dutasteride and finasteride for benign prostatic hyperplasia, reporting that while symptom improvements are similar, dutasteride may reduce prostate surgery risk and acute urinary retention more effectively.
5 citations
,
June 2020 in “Journal of Endocrinological Investigation” The study observed that women with congenital adrenal hyperplasia experience more impaired sexual functions and are more often homosexually or bisexually oriented than those with polycystic ovary syndrome.
October 2015 in “Annals of Internal Medicine” Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.
1 citations
,
July 2024 in “Journal of Assisted Reproduction and Genetics”
April 2018 in “The Journal of Urology” In this study, men with pre-diabetes seeking treatment for erectile dysfunction had worse hormonal and metabolic profiles and a higher risk of severe erectile dysfunction compared to those without pre-diabetes.
May 2023 in “IntechOpen eBooks” This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.
14 citations
,
February 2018 in “Psychoneuroendocrinology” This study found that male 5α-reductase 2 knockout mice showed deficits in social dominance behaviors and reduced dopamine receptor binding in a brain region related to social ranking.
30 citations
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November 2000 in “British Journal of Cancer” This study found that certain endocrine factors, influenced by smoking, birth order, and frequency of orgasms, may play an important role in the development of male breast cancer.
April 2020 in “The FASEB Journal” This study found that disrupting testosterone biosynthesis in male rats mitigated cardiovascular and autonomic impairments caused by endotoxemia, indicating testosterone's significant role in these conditions.