TLDR Testosterone levels influence male behaviors and physical traits, but this relationship is complex and influenced by both internal and external factors.
The review from March 2001 discussed the relationship between testosterone levels and male physical and behavioral characteristics, highlighting the methodological issues in measuring testosterone and the complexity of its physiological effects. It emphasized that testosterone levels are affected by both hormone-driven conditions and external factors beyond hormonal or individual control. The review also noted that while behavior can be influenced by the environment, androgens can reinforce certain behaviors, which in turn can affect testosterone secretion. The authors cautioned against generalizing or individualizing study results, as this could lead to doubtful conclusions and prejudices. They advised that results should be interpreted with caution to avoid oversimplification and overinterpretation.
581 citations,
October 1998 in “Journal of The American Academy of Dermatology” Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
18 citations,
May 1992 in “American Journal of Biological Anthropology” Higher androgen levels do not cause baldness in men.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
18 citations,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
8 citations,
August 2020 in “Clinical and Experimental Dermatology” Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
