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research The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis
In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.
research Male hormonal contraception: looking back and moving forward
This review discusses the physiological basis, history, and current development of male hormonal contraception, highlighting its potential risks and benefits, but reports no new research findings.
research Low serum zinc concentration is associated with low serum testosterone but not erectile function
In this study, researchers observed that lower serum zinc concentrations were associated with decreased serum testosterone levels, but no link was found with sexual function questionnaire scores.
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
research Safety and efficacy of platelet-rich plasma injection for treatment of erectile dysfunction: a prospective randomized controlled study
This study found no significant evidence supporting the effectiveness of platelet-rich plasma injections for treating mild-to-moderate erectile dysfunction compared to placebo.
research Platelet-rich plasma for erectile dysfunction: a review of the current research landscape
This review reports that while intracavernosal platelet-rich plasma is considered safe for treating erectile dysfunction, its efficacy remains unclear due to variable clinical trial protocols.
research Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens
This study found that penile and clitoral differentiation in mice is influenced by androgen exposure, with penile features developing postnatally requiring prenatal and ongoing androgen presence.
research Endocrinology, Brain, and Pituitary Gland
This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.
research Local stimulation of sebaceous gland activity by the topical administration of dehydroepiandrosterone
In this study, topical dehydroepiandrosterone (DHEA) doubled sebum production in women without systemic side effects, suggesting it may be a safe treatment for reduced sebum output related to menopause.
research Organic Causes of Erectile Dysfunction in Men Under 40
This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.
research Extraordinary Urinary Frequency
This reply argues that children with isolated extraordinary daytime frequency do not require extensive testing or aggressive pharmacologic treatments, noting potential negative effects of oxybutynin.
research Determinants of Plasma Androgen and Estrogen Levels in Men
This article discusses the testosterone and estradiol levels in men, examining their roles and suggesting the need for better understanding to differentiate between normal and abnormal levels related to androgen deficiency symptoms, without reporting new clinical results.
research Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men
This study found that three genetic loci, including the newly identified JMJD1C, are associated with circulating testosterone and dihydrotestosterone levels, explaining a small portion of their variance in European men.
research Moisturizers, Lubricants, and Vulvar Hygiene Products: Issues, Answers, and Clinical Implications
This review summarizes characteristics of vaginal moisturizers, lubricants, and washes for managing genitourinary syndrome of menopause, and clarifies common misconceptions about their chemical additives, without providing new clinical results.
research Hyperandrogenism and woman's sexual function
This study found no significant relationship between hormone levels and sexual function in hirsute young women compared to a control group.
research 1194: The Long Term Effects of Doxazosin, Finasteride, and the Combination on Sexual Function in Men Participating in the MTOPS Study
Doxazosin and finasteride negatively affect sexual function in men with BPH.
research 1304 Assessing Post Operative Continuation of LUTs Medication Following TURP and BiPolep
This study found that a substantial number of patients continued tamsulosin and/or finasteride unnecessarily after prostate surgery, with poor documentation and communication contributing to this issue.
research PD49-03 IS TADALAFIL ASSOCIATED WITH DECREASED RISK OF MAJOR ADVERSE CARDIAC EVENTS OR VENOUS THROMBOEMBOLISM IN MEN WITH LOWER URINARY TRACT SYMPTOMS?
This study found that tadalafil use was associated with a decreased risk of major adverse cardiac events and venous thromboembolism in men with lower urinary tract symptoms.
research Finasteride and male fertility
Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
research [Effect of selective 5alpha-reductase inhibitor or/and testosterone undecanoate on the reproductive function of male rats].
This study suggests that the negative impact of high-dose Finasteride on male reproductive function may be mitigated by concurrent administration with TU.
research Sex‐dependent responsiveness of hippocampal neurons to sex neurosteroids: A role of Arc/Arg3.1
This study found that Arc/Arg3.1 expression in hippocampal neurons is regulated by sex steroids in a sex-dependent manner, with E2 increasing expression in females and DHT in males.
research Histology, lectin histochemistry and ultrastructure of interdigital gland in crossbred sheep
This study investigated the interdigital glands in sheep, highlighting their apocrine sweat glands' ultrastructural characteristics and positive lectin reaction, but reported no new clinical results.
research 5-Aminolevulinic acid improves chicken sperm motility
This study found that 5-aminolevulinic acid significantly improved chicken sperm motility and increased mitochondrial membrane depolarization, while decreasing ATP levels.
research Mechanisms of testosterone action
This study reports that testosterone requires conversion to DHT and estradiol for its various actions on external genitalia and bone, influencing lean mass, muscle size, strength, and body fat in hypogonadal males.
research Salivary testosterone levels in infertile men
This study found that salivary testosterone levels were significantly lower in oligospermic and azoospermic men compared to normal men, suggesting its potential use in assessing male androgen status.
research Platelet-Rich Plasma for Urologic Conditions: An Early Call for Composition Reporting
The conclusion is that future trials should report specific details about the PRP composition to better understand its effects on urologic conditions.
research Continued improvement in pressure-flow parameters in men receiving finasteride for 2 years
This study found that finasteride improved urodynamic measures of obstruction in men with benign prostatic enlargement and lower urinary tract symptoms, with continued improvement over two years of treatment.
research (122) Erectile Hemodynamics Asessment In ED Patients With Self-Diagnosed Post-finasteride syndrome (PFS)
In this study, researchers found no evidence of hemodynamic alterations associated with erectile dysfunction in men self-diagnosed with post-finasteride syndrome following the use of finasteride for hair loss.
research Introduction
This review discusses rare and controversial conditions like painful nocturnal erections and post-finasteride syndrome, calling attention to these issues but providing no new clinical findings.