Platelet-Rich Plasma for Urologic Conditions: An Early Call for Composition Reporting

    November 2023 in “ The Journal of Urology ”
    Daniel S. Greenberg, Evan J. Panken, Channa Amarasekera
    Image of study
    TLDR The conclusion is that future trials should report specific details about the PRP composition to better understand its effects on urologic conditions.
    Platelet-rich plasma (PRP), a blood product with high platelet concentrations, has been introduced as a potential treatment for urologic conditions like Peyronie’s disease and erectile dysfunction (ED). Three randomized, double-blind, placebo-controlled clinical trials have been conducted on adult men with mild-to-moderate ED, using PRP injections. However, the results are conflicting, with two studies showing significant benefits of PRP compared to placebo, while one showed no difference. The authors suggest that the conflicting results may be due to differences in patient population, use of phosphodiesterase 5 inhibitors, and variations in the injected volume of PRP. They also highlight a key missing aspect in PRP trial design: patients’ platelet concentration at baseline, the platelet increase factor in their PRP, and growth factor and cytokine concentrations of the injected treatment. They call for future trials to report these factors, as they can significantly impact the interpretation and clinical implications of the findings.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 77 results

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  14 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 weeks ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Why can't you drink caffeine after PRP?

      in Treatment  9 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  549 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 1 year ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

      in Treatment  90 upvotes 4 years ago
      Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

    Similar Research

    5 / 1000+ results