TLDR Finasteride improves urinary function in men for 2 years.
A number of studies have found that finasteride is an effective treatment for men with benign prostatic enlargement and lower urinary tract symptoms. The drug can improve pressure-flow parameters and lead to continued improvement in urinary function over a 2-year period. The improvement is particularly significant in men with larger prostate volumes at the beginning of the study. However, the clinical significance of these changes is unclear, and more research is needed to understand the long-term effects of alpha-blocker therapy on urodynamic function.
1054 citations,
February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
211 citations,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively treats BPH, but needs more trials to understand potential.
1707 citations,
December 2003 in “The New England Journal of Medicine” Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
1054 citations,
February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
728 citations,
August 1996 in “The New England Journal of Medicine” Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
