research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
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research Potassium Channel Therapeutics at the Bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research BMP2 And BMP7 Play Antagonistic Roles In Feather Induction
BMP2 and BMP7 have opposite roles in feather formation.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables
Mutant mice help researchers understand hair growth and related genetic factors.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research EDA2R Is Associated With Androgenetic Alopecia
EDA2R gene linked to hair loss.
research Strategies to Enhance Epithelial-Mesenchymal Interactions for Human Hair Follicle Bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Diagnostic Criteria for Polycystic Ovarian Syndrome
To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Neuroendocrinology of Epithelial Hair Follicle Stem Cells
Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
research Novel Cosmeceuticals from Plants: An Industry-Guided Review
Plant-based ingredients are effective and safe for modern skincare products.
research Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice
Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research WNT10A, Dermatology and Dentistry
Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China
Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats
lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research Distinct Mechanisms Underlie Pattern Formation in the Skin and Skin Appendages
Different processes create patterns in skin and things like hair and feathers.
research Potassium Channel Openers: Therapeutic Potential in Cardiology and Medicine
Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration of Laboratory and Spiny Mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Transcriptomic Regulation of Seasonal Coat Color Change in Hares
Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
research Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration
Stem cells can help regenerate hair follicles.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.