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Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

No treatment fully prevents hair loss from chemotherapy yet.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

BMP2 and BMP7 have opposite roles in feather formation.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Mutant mice help researchers understand hair growth and related genetic factors.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Follistatin helps hair growth and cycling, while activin prevents it.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Human hair follicles can regenerate after removal, but with low success rate.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.