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In this case study, a patient with moderate papulopustular acne showed improvement in acne scars and active lesions after three monthly treatments with autologous plasma-rich growth factors, which help regulate inflammation, inhibit bacterial growth, and restore collagen.

This study found that interleukin-1α and interleukin-7 secreted by keratinocytes enhance the proliferation of γδT-cells and epidermal stem cells, revealing mechanisms of stem cell activation during wound healing in mice.

This study found that regulatory T cells accumulate in hair follicle epithelium via the Cxcr4-Cxcl12 axis, partially influenced by glucocorticoid receptor signaling, promoting hair regeneration; similar mechanisms were observed in human and murine skin.

This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.

In this study, upper-bulge epidermal stem cells in mouse hair follicles were shown to play a role in forming tactile sensory units by creating an extracellular matrix that supports nerve interactions.

In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.

This study found that combining ultrapulsed fractional CO2 laser with bovine basic fibroblast growth factor significantly improved acne scars more effectively and safely compared to laser therapy alone.

This study found that transgenic mice overexpressing HGF/SF are more susceptible to UVA-induced melanoma, with melanin in the papillary dermis interacting with UVA to induce melanoma.

This study suggests that hepatocyte growth factor (HGF) may play a role in hair follicle neogenesis and that an HGF mimetic could enhance skin substitute development.

This study found that GFRα2 influences cell size but not survival or target innervation of Ret-positive low-threshold mechanoreceptors in mouse dorsal root ganglia, differing from its role in nonpeptidergic nociceptors.

This study found that certain polymorphisms in EGF and EGFR genes may increase susceptibility to alopecia areata in the Korean population, and these genetic variations could be associated with specific symptoms such as nail involvement and body hair loss.

This study found that insulin-like growth factor-I and hepatocyte growth factor increased the chemotactic migration of human hair outer root sheath cells, suggesting these factors have both growth stimulatory and chemotactic effects.

This study found that epidermal growth factor and fibroblast growth factor accelerated proliferation of human hair bulb papilla cells and root sheath fibroblasts cultured in vitro.

A cancer patient died from a severe skin reaction after taking the drug cetuximab.

This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.

FGF18 controls hair growth rest phase.

This study found that a key gene signature, including FGF11, highlights the immunologic nature of keloid lesions, distinguishing them from normal fibroblasts and scars.

In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.

In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.

This study found that cepharanthine can inhibit gastric cancer cell activity by inducing oxidative stress and altering energy metabolism, suggesting its potential for gastric cancer treatment.

This review discusses the classification, pathogenesis, and management of skin, hair, nail, and mucosal changes due to EGFR inhibitors, emphasizing the importance of informing patients to improve therapy compliance.

This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.

In this study, RNA-sequencing identified differentially expressed genes, including FGF5, FGFR1, and RRAS, that affect the hair follicle growth cycle in Inner Mongolian Cashmere goats.

This study demonstrated that disrupting EGFR signaling in mice leads to immune sensitivity compromising the hair follicle's protective environment, but JAK1/2 inhibition can restore this immune privilege and stimulate hair growth, suggesting a potential therapy for scarring hair loss diseases like cicatricial alopecia.

In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.

In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.

ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

In this study, Gsdma1/2/3 knockout mice showed reduced epidermal hyperplasia and inflammation when induced by PMA, which was attributed to decreased EGFR-Stat3/Akt signaling due to a decrease in related ligands.