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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

JAK inhibitors can effectively reverse hair loss in people with alopecia areata.

New therapies are being developed that target integrin pathways to treat various diseases.

Vitamin A affects hair loss and immune response in alopecia areata.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Cryotherapy helps reduce chemotherapy side effects but needs more research for best use.

Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Treating H. pylori infection might help cure alopecia areata.

Linagliptin slows down premature aging in certain mice.

HLA-DRB5 and other genes may be linked to alopecia universalis.

JAK inhibitors show promise for treating hair loss in alopecia areata but need more clinical trials to confirm safety and effectiveness.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

The mouse hairy ears mutation causes longer ear hair due to changes in gene expression.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.

New genetic mutations linked to rare skin disorders were found in three newborns.

A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.

PRP therapy helps skin heal and improve by promoting cell growth and repair.

MG53 helps reduce skin damage caused by nitrogen mustard.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.