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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride doesn't harm bone density in older men with BPH.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

The surgical technique of scalp advancement and pretrichial brow lift shortens the forehead and lifts brows, is good for women and transgender women with high foreheads, but not recommended for men and has some risks.

A circular RNA helps cashmere goat hair cells become hair follicles by blocking a molecule to boost a gene important for hair growth.

A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

Finasteride doesn't affect bone density in male rats.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Oral dutasteride improves hair growth, reduces hair loss, and is safe for most patients.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Regal Hair Salon records gift card sales as liabilities and recognizes revenue when redeemed.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Hair stiffness is higher when it has more para-like cortical cells.

Serenoa repens may cause early puberty and should be used cautiously in children.

Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Dupilumab can improve both atopic dermatitis and alopecia universalis.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

CaV1.2 helps activate hair follicle stem cells without calcium flux.

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.