research A Novel NR5A1 Gene Mutation Causing 46, XY DSD Without Adrenal Insufficiency in an Immigrant Boy from Dominican Republic
A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.
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research 46,XY DSD Due to Impaired Androgen Production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research 46,XY Disorders of Sex Development Due to Type 2 5-Alpha Reductase Deficiency in Three Siblings: A Case Report from a Low-Resource Setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
research The Laboratory in the Multidisciplinary Diagnosis of Differences or Disorders of Sex Development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Disorders of Sex Development
DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
research 46, XY Disorder of Sexual Development with Ambiguous Female External Genitalia: A Case Report
A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.
research Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development
Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
research Evidence for Multiple, Developmentally Regulated Isoforms of Ptprq on Hair Cells of the Inner Ear
Ptprq has multiple forms that change during inner ear development.
research In Vivo Hair Re-Growth Efficacies of Minoxidil Preparations: Distearyldimethylammonium Chloride Vesicles, Cellulose Acetate Phthalate Microparticles, and Poloxamer Solution
Minoxidil in distearyldimethylammonium chloride vesicles significantly promotes hair growth, while minoxidil in microparticles or poloxamer solutions doesn't.
research A Teenage Girl with Unexpected Pubertal Changes
The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
research Systemic Lupus Erythematosus in Men
Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.
research Infliximab Induced Lupus in Crohn's Disease
Infliximab can trigger lupus-like symptoms in Crohn's disease patients.
research Current and Future Perspectives on Clinical Management of Classic 21-Hydroxylase Deficiency
Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.
research The Plastic and Functional Changes in Hippocampal Neurons During Pregnancy, Delivery, and Postpartum Are Reversed by Offspring Deprivation
Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.
research Physiology of Male Gonadotropic Axis and Disorders of Sex Development
Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
research Genetic Defects of Female Sexual Differentiation
Genetic mutations can affect female sexual development, requiring personalized medical care.
research Telogen Effluvium Therapy in SLE with 2% Minoxidil and Oral Antioxidants: A Case Report
Minoxidil and oral antioxidants helped improve hair growth in a patient with hair loss due to lupus.
research Immunotherapeutic Effects of Allogeneic Mesenchymal Stem Cells on Systemic Lupus Erythematosus
Early treatment with the right dose of stem cells can reduce lupus symptoms.
research Clinical and Immunological Characteristics of 56 Patients with Systemic Lupus Erythematosus in Uganda
SLE is rare in Uganda but often has complications and overlaps with rheumatoid arthritis.
research Late Onset Systemic Lupus Erythematosus: Clinical and Autoantibody Profile Compared with Young Onset Systemic Lupus Erythematosus
Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.
research Immune Thrombocytopenia as the Initial Manifestation of Pediatric Systemic Lupus Erythematosus: Case Reports
A child with low platelets and anemia was later found to have lupus.
research GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus
Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Immune-Mediated Coombs Negative Intravascular Hemolysis in Systemic Lupus Erythematosus
A woman with lupus had blood cell destruction, treated successfully with medication.
research Characteristics of Pregnancy with Systemic Lupus Erythematosus (SLE) in Dr. Mohammad Hoesin Hospital, Palembang
Most pregnancies with SLE resulted in intrauterine growth restriction (IUGR).
research Autoantibodies in Pediatric SLE: Cluster Analysis and Clinical Associations, a Single Center Cohort Study
Different autoantibody groups in pediatric SLE are linked to specific symptoms and disease outcomes.
research Clinical Analysis of Rash in Systemic Lupus Erythematosus
Rash in SLE patients indicates more severe disease.
research Comparison of Clinical Characteristics Among Different Times of Disease Onset in Patients with Systemic Lupus Erythematosus
Juvenile-onset lupus patients have more severe symptoms and need stronger treatment.
research Detection of Subtypes of T Helper Cells and Their Cytokines in Peripheral Blood of Patients with Systemic Lupus Erythematosus and Their Clinical Significances
Higher levels of certain immune cells and proteins are linked to more severe lupus symptoms.