GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

    April 2023 in “ Research Square (Research Square) ”
    Fangyuan Yang, Liuying Li, Huijuan Liu … Erwei Sun

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that lower GPX4 mRNA levels in polymorphonuclear neutrophils of systemic lupus erythematosus patients were negatively associated with disease activity and serological markers, suggesting a diagnostic value for GPX4 mRNA.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on researchsquare.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Trichoscopic Signs in Systemic Lupus Erythematosus: A Comparative Study with 109 Patients and 305 Healthy Controls Journal of the European Academy of Dermatology and Venereology · 2019
    2. Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus American Journal of Clinical Dermatology · 2018
    3. Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus: Clinical and Histopathological Analysis of Four Cases Journal of the European Academy of Dermatology and Venereology · 2011