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GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

research GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

April 2023 in “Research Square (Research Square)”

Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.

research Trichoscopic Signs in Systemic Lupus Erythematosus: A Comparative Study with 109 Patients and 305 Healthy Controls

29 citations, January 2019 in “Journal of the European Academy of Dermatology and Venereology”

Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.

research Measures of Adult Systemic Lupus Erythematosus: Disease Activity and Damage

44 citations, October 2020 in “Arthritis Care & Research”

Choosing the right tools is crucial for accurately measuring lupus activity and damage.

research Outcome Measures in Cutaneous Autoimmune Disease: Dermatomyositis and Lupus Erythematosus

2 citations, January 2006 in “Technical report”

The document concludes that better tools are needed to measure skin disease severity in dermatomyositis and cutaneous lupus erythematosus, and introduces the DSSI and CLASI as reliable instruments.

research Validation of the Cutaneous Lupus Disease Area and Severity Index Using Physician- and Patient-Assessed Health Outcome Measures

40 citations, October 2012 in “Journal of the American Academy of Dermatology”

CLASI is a valid tool for assessing skin activity and damage in lupus patients.

View more "sle disease activity index" in research →

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community Fin/dut increase in estrogen and autoimmune diseases

in Chat 6 upvotes 1 year ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community I don’t know what to do at this point

in Female 83 upvotes 4 days ago

A 21-year-old woman with female pattern baldness has tried minoxidil, red light therapy, and supplements without success. She is considering spironolactone and seeking medical advice.