Telogen Effluvium Therapy in SLE with 2% Minoxidil and Oral Antioxidants: A Case Report

    September 2022 in “ Health and Medical Journal ”
    Eka Devinta Novi Diana, Niluh Wijayanti, Prasetyadi Mawardi
    TLDR Minoxidil and oral antioxidants helped improve hair growth in a patient with hair loss due to lupus.
    The document reports a case of a 19-year-old female patient with telogen effluvium (ET), a hair disorder characterized by excessive shedding of telogen hair, triggered by systemic lupus erythematosus (SLE). The patient, who had been experiencing hair loss for a year, presented with symptoms of SLE including fever, facial rash, and joint pain, and was diagnosed with SLE based on positive ANA, dsDNA, Scl-70, and Ro-60 tests. She was treated with methylprednisolone (48 mg/day) and cyclosporine (100 mg/day). Dermatological examination showed diffuse hair loss and a positive hair pull test. Treatment with topical 2% minoxidil twice daily and oral antioxidants containing keratin (cynatine HNS) at 250 mg twice daily was initiated. The treatment led to new hair growth and increased hair density by day 90. The document concludes that topical minoxidil, a vasodilator, and oral antioxidants containing keratin can be considered as a combined therapy for ET, as they improve blood flow and oxygen to hair follicles and enhance hair, skin, and nail health.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 639 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How many of you guys have taken accutane?

      in Chat  8 upvotes 8 months ago
      Accutane may accelerate hair loss in genetically predisposed individuals by affecting enzymes related to DHT metabolism. Some users report hair loss after taking Accutane, while others use treatments like finasteride and minoxidil to manage hair loss.

      community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

      in Research/Science  6 upvotes 5 months ago
      Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

      community Hair loss over a year following depression and taking antidepressants

      in Side effects?  184 upvotes 2 days ago
      A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

    Similar Research

    5 / 1000+ results